Microneedling with Kimera-Exosomes

Xo Glo®

Purified MSC Exosomes

XoGlo® is a purified mesenchymal stem cell (MSC)-derived exosome product that contains a multitude of growth factors that can enhance the coordinated cascade of cellular and biochemical events involved in natural wound healing and skin rejuvenation.

The physiologic effects of the exosomal growth factors in XoGlo® can be used to rejuvenate collagen in aging and reduce inflammation. XoGlo® has the potential to improve skin texture, reduce scarring, stimulate hair growth and shorten recovery time cosmetic surgery.

XoGlo® is a cell-free isolate of MSC exosomes. This concentrated biologic product is sterile-filtered and re-suspended in [0.9%] normal saline. Each milliliter of XoGlo® contains 1 billion MSC exosomes.



  • Stimulate fibroblast proliferation and migration;
  • Increase collagen extracellular matrix production/deposition;
  • Regulate tissue remodeling to reduce scarring;
  • Increase the number of hair follicles in the growth phase;
  • Regenerate dermal papilla cells of hair follicle.


MSC exosomes down-regulate inflammatory proteins and upregulate anti-in-flammatory proteins.


upregulate anti-in-flammatory proteins.


Exosomes stimulate the proliferation and migration of cells such as fibroblasts, endothelial cells, keratinocytes and specific endogenous progenitor cells. This increases angiogenesis (new blood vessel formation), improves survival of

damaged tissues and reduces scarring.


Exosomes derived from mesenchymal stem cells have been shown to reduce apoptosis (programmed cell death), which could lead to less tissue damage in response to disease or injury. MSC Exosomes have the capacity to enhance tissue remodeling by promoting a normal lattice-structure of collagen fibers for reduced scarring and more normal healing.



Perfect for someone that doesn't want their blood drawn, wants amazing results and wants to heal a bit quicker.

Exosomes are applied directly to the epidermis of the skin using RejuvapenNXT (FDA cleared) during microneedling.  RejuvapenNXT creates hundreds to thousands of “micro” channels per second to stimulate the skin’s natural wound healing process to prompt tissue remodeling without causing scar tissue formation. The rapid release of growth factors in Exosomes promotes the body’s natural healing process. This leads to an improvement in both the appearance and texture of your skin by stimulating collagen and elastin production.  Exosomes, from Kimera Labs, work to revitalize, activate, and recruit the area being targeted by reducing inflammation and jump starting the body’s natural healing process.